Explorer
Tchem targets
120 receptors match — sorted by development interest.
Class
Development
System
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| Gene | Receptor | Class | Family | Structures | Ligands | TDL | Dev. interest |
|---|---|---|---|---|---|---|---|
| KISS1R | kisspeptin receptor | A | Kisspeptin receptors | 5 | 629 | Tchem | 55 |
| CXCR2 | CXCR2 | A | Chemokine receptors | 3 | 908 | Tchem | 55 |
| GRM5 | mGlu₅ receptor | C | Metabotropic glutamate receptors | 21 | 919 | Tchem | 55 |
| CCR1 | CCR1 | A | Chemokine receptors | 3 | 916 | Tchem | 54 |
| GRM1 | mGlu₁ receptor | C | Metabotropic glutamate receptors | 3 | 895 | Tchem | 53 |
| CCR6 | CCR6 | A | Chemokine receptors | 3 | 669 | Tchem | 52 |
| F2RL1 | PAR2 | A | Proteinase-activated receptors | 3 | 468 | Tchem | 51 |
| FFAR4 | FFA4 receptor | A | Free fatty acid receptors | 12 | 905 | Tchem | 51 |
| GRM2 | mGlu₂ receptor | C | Metabotropic glutamate receptors | 23 | 923 | Tchem | 51 |
| CCR3 | CCR3 | A | Chemokine receptors | 1 | 923 | Tchem | 50 |
| CXCR3 | CXCR3 | A | Chemokine receptors | 6 | 917 | Tchem | 50 |
| FPR2 | FPR2/ALX | A | Formylpeptide receptors | 9 | 942 | Tchem | 50 |
| NPY1R | Y₁ receptor | A | Neuropeptide Y receptors | 6 | 511 | Tchem | 50 |
| GRM3 | mGlu₃ receptor | C | Metabotropic glutamate receptors | 8 | 445 | Tchem | 50 |
| CCKBR | CCK₂ receptor | A | Cholecystokinin receptors | 5 | 913 | Tchem | 49 |
| NTSR1 | NTS₁ receptor | A | Neurotensin receptors | 8 | 901 | Tchem | 49 |
| OPRL1 | NOP receptor | A | Opioid receptors | 4 | 909 | Tchem | 49 |
| APLNR | apelin receptor | A | Apelin receptors | 14 | 926 | Tchem | 49 |
| SSTR4 | SST4 receptor | A | Somatostatin receptors | 2 | 925 | Tchem | 49 |
| NPY2R | Y₂ receptor | A | Neuropeptide Y receptors | 5 | 916 | Tchem | 48 |
| MCHR1 | MCH₁ receptor | A | Melanin-concentrating hormone | 10 | 924 | Tchem | 48 |
| GRM7 | mGlu₇ receptor | C | Metabotropic glutamate receptors | 1 | 418 | Tchem | 48 |
| CCR9 | CCR9 | A | Chemokine receptors | 1 | 636 | Tchem | 48 |
| GPR119 | GPR119 | A | GPR18, GPR55 and GPR119 | 7 | 919 | Tchem | 47 |
| CCR8 | CCR8 | A | Chemokine receptors | 6 | 488 | Tchem | 46 |
| TACR2 | NK₂ receptor | A | Tachykinin receptors | 1 | 912 | Tchem | 46 |
| GALR1 | GAL₁ receptor | A | Galanin receptors | 2 | 257 | Tchem | 45 |
| F2RL3 | PAR4 | A | Proteinase-activated receptors | — | 905 | Tchem | 45 |
| RXFP1 | RXFP1 | A | Relaxin family peptide receptors | 1 | 853 | Tchem | 44 |
| ADCYAP1R1 | PAC₁ receptor | B1 | VIP and PACAP receptors | 5 | 227 | Tchem | 44 |
| GPR88 | GPR88◇ | A | Class A orphans | 2 | 759 | Tchem | 44 |
| CMKLR1 | chemerin receptor | A | Chemerin receptor | 2 | 568 | Tchem | 43 |
| GRM4 | mGlu₄ receptor | C | Metabotropic glutamate receptors | 4 | 524 | Tchem | 43 |
| FFAR2 | FFA2 receptor | A | Free fatty acid receptors | 5 | 907 | Tchem | 43 |
| GRPR | BB₂ receptor | A | Bombesin receptors | 4 | 481 | Tchem | 43 |
| GPR84 | GPR84◇ | A | Class A orphans | 4 | 909 | Tchem | 43 |
| VIPR2 | VPAC₂ receptor | B1 | VIP and PACAP receptors | 2 | 186 | Tchem | 43 |
| TRHR | TRH₁ receptor | A | Thyrotropin-releasing hormone receptors | 4 | 26 | Tchem | 42 |
| NPY5R | Y₅ receptor | A | Neuropeptide Y receptors | — | 913 | Tchem | 42 |
| GPR139 | GPR139◇ | A | Class A orphans | 4 | 699 | Tchem | 42 |
| BRS3 | BB₃ receptor | A | Bombesin receptors | 2 | 352 | Tchem | 42 |
| CCR7 | CCR7 | A | Chemokine receptors | 1 | 46 | Tchem | 42 |
| LTB4R | BLT₁ receptor | A | Leukotriene receptors | 2 | 796 | Tchem | 42 |
| NMUR2 | NMU2 receptor | A | Neuromedin U receptors | 3 | 275 | Tchem | 41 |
| PROKR1 | PKR₁ | A | Prokineticin receptors | — | 655 | Tchem | 41 |
| FZD7 | FZD₇ | F | Frizzled | 4 | 75 | Tchem | 41 |
| GRM6 | mGlu₆ receptor | C | Metabotropic glutamate receptors | — | 242 | Tchem | 40 |
| SUCNR1 | succinate receptor | A | Succinate receptors | 7 | 204 | Tchem | 40 |
| PROKR2 | PKR₂ | A | Prokineticin receptors | — | 23 | Tchem | 40 |
| NPSR1 | NPS receptor | A | Neuropeptide S receptors | — | 592 | Tchem | 40 |
| GPR6 | GPR6◇ | A | Class A orphans | 4 | 501 | Tchem | 39 |
| GPR52 | GPR52◇ | A | Class A orphans | 5 | 763 | Tchem | 39 |
| FZD4 | FZD₄ | F | Frizzled | 3 | 3 | Tchem | 39 |
| GALR2 | GAL₂ receptor | A | Galanin receptors | 4 | 288 | Tchem | 39 |
| LGR4 | LGR4◇ | A | Class A orphans | 9 | 6 | Tchem | 38 |
| CCRL2 | CCRL2 | A | Chemokine receptors | — | 307 | Tchem | 38 |
| NMUR1 | NMU1 receptor | A | Neuromedin U receptors | 2 | 255 | Tchem | 38 |
| CXCR5 | CXCR5 | A | Chemokine receptors | — | 155 | Tchem | 38 |
| NMBR | BB₁ receptor | A | Bombesin receptors | 1 | 312 | Tchem | 37 |
| HCAR3 | HCA₃ receptor | A | Hydroxycarboxylic acid receptors | 4 | 239 | Tchem | 37 |
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