LGR4
ATchemOrphanLGR4
Rhodopsin· Class A orphans· 951 aa
Development interest
38/ 100
Tchem
A potent ligand exists, but no approved drug.
413 refs·6 ligands·9 structures
Disease evidence
×15%
Literature
×30%
Structures
×15%
Ligands
×20%
Approved drugs
×20%
Signalling
Signal transduction
Primary G-protein coupling is not curated for LGR4 in Helix7. See GPCRdb couplings for transducer data on this receptor.
At a glance
Key facts
- Structures
- 9
- Distinct ligands
- 6
- Approved drugs
- 0
- Disease links
- 3386
- Organ systems
- 11
- Citations
- 413
AdiposeCardiovascularDigestiveEndocrineImmuneIntegumentaryMusculoskeletalNervousReproductiveRespiratoryUrinary
Sources & attribution
GPCRdbCC BY 4.0Human Protein AtlasCC BY-SA 4.0IUPHAR/BPS Guide to PHARMACOLOGYCC BY-SA 4.0ChEMBLCC BY-SA 4.0PubChem BioAssayPublic domainOpen Targets PlatformCC0 1.0
Data redistributed under each source's licence. See Citation & licenses.