OPRL1
ATchemNOP receptor
Rhodopsin· Opioid receptors· 370 aa
Development interest
49/ 100
Tchem
A potent ligand exists, but no approved drug.
603 refs·909 ligands·4 structures
Ligands
×20%
Literature
×30%
Disease evidence
×15%
Structures
×15%
Approved drugs
×20%
Signalling
Signal transduction
Primary G-protein transducer(s):
Gi/Goprimary
Canonical coupling; some receptors also signal through secondary transducers and β-arrestin. See GPCRdb couplings for full data.
At a glance
Key facts
- Structures
- 4
- Distinct ligands
- 909
- Approved drugs
- 0
- Disease links
- 725
- Organ systems
- 7
- Citations
- 603
CardiovascularDigestiveEndocrineImmuneNervousReproductiveRespiratory
Sources & attribution
GPCRdbCC BY 4.0Human Protein AtlasCC BY-SA 4.0IUPHAR/BPS Guide to PHARMACOLOGYCC BY-SA 4.0ChEMBLCC BY-SA 4.0PubChem BioAssayPublic domainOpen Targets PlatformCC0 1.0
Data redistributed under each source's licence. See Citation & licenses.