GRM3
CTchemmGlu3 receptor
Glutamate· Metabotropic glutamate receptors· 879 aa
Development interest
50/ 100
Tchem
A potent ligand exists, but no approved drug.
262 refs·445 ligands·8 structures
Ligands
×20%
Disease evidence
×15%
Literature
×30%
Structures
×15%
Approved drugs
×20%
Signalling
Signal transduction
Primary G-protein transducer(s):
Gi/Goprimary
Canonical coupling; some receptors also signal through secondary transducers and β-arrestin. See GPCRdb couplings for full data.
At a glance
Key facts
- Structures
- 8
- Distinct ligands
- 445
- Approved drugs
- 0
- Disease links
- 326
- Organ systems
- 1
- Citations
- 262
Nervous
Sources & attribution
GPCRdbCC BY 4.0Human Protein AtlasCC BY-SA 4.0IUPHAR/BPS Guide to PHARMACOLOGYCC BY-SA 4.0ChEMBLCC BY-SA 4.0PubChem BioAssayPublic domainOpen Targets PlatformCC0 1.0
Data redistributed under each source's licence. See Citation & licenses.