FZD4
FTchemFZD4
Frizzled· Frizzled· 537 aa
Development interest
39/ 100
Tchem
A potent ligand exists, but no approved drug.
484 refs·3 ligands·3 structures
Disease evidence
×15%
Literature
×30%
Structures
×15%
Ligands
×20%
Approved drugs
×20%
Signalling
Signal transduction
Primary G-protein coupling is not curated for FZD4 in Helix7. See GPCRdb couplings for transducer data on this receptor.
At a glance
Key facts
- Structures
- 3
- Distinct ligands
- 3
- Approved drugs
- 0
- Disease links
- 2655
- Organ systems
- 11
- Citations
- 484
AdiposeCardiovascularDigestiveEndocrineImmuneIntegumentaryMusculoskeletalNervousReproductiveRespiratoryUrinary
Sources & attribution
GPCRdbCC BY 4.0Human Protein AtlasCC BY-SA 4.0IUPHAR/BPS Guide to PHARMACOLOGYCC BY-SA 4.0ChEMBLCC BY-SA 4.0Open Targets PlatformCC0 1.0
Data redistributed under each source's licence. See Citation & licenses.