GPR6
ATchemOrphanGPR6
Rhodopsin· Class A orphans· 362 aa
Development interest
39/ 100
Tchem
A potent ligand exists, but no approved drug.
73 refs·501 ligands·4 structures
Ligands
×20%
Literature
×30%
Structures
×15%
Disease evidence
×15%
Approved drugs
×20%
Signalling
Signal transduction
Primary G-protein coupling is not curated for GPR6 in Helix7. See GPCRdb couplings for transducer data on this receptor.
At a glance
Key facts
- Structures
- 4
- Distinct ligands
- 501
- Approved drugs
- 0
- Disease links
- 70
- Organ systems
- 2
- Citations
- 73
EndocrineNervous
Sources & attribution
GPCRdbCC BY 4.0Human Protein AtlasCC BY-SA 4.0IUPHAR/BPS Guide to PHARMACOLOGYCC BY-SA 4.0ChEMBLCC BY-SA 4.0Open Targets PlatformCC0 1.0
Data redistributed under each source's licence. See Citation & licenses.