NPY1R
ATchemY1 receptor
Rhodopsin· Neuropeptide Y receptors· 384 aa
Development interest
50/ 100
Tchem
A potent ligand exists, but no approved drug.
1,256 refs·511 ligands·6 structures
Ligands
×20%
Literature
×30%
Disease evidence
×15%
Structures
×15%
Approved drugs
×20%
Signalling
Signal transduction
Primary G-protein transducer(s):
Gi/Goprimary
Canonical coupling; some receptors also signal through secondary transducers and β-arrestin. See GPCRdb couplings for full data.
At a glance
Key facts
- Structures
- 6
- Distinct ligands
- 511
- Approved drugs
- 0
- Disease links
- 323
- Organ systems
- 11
- Citations
- 1,256
AdiposeCardiovascularDigestiveEndocrineImmuneIntegumentaryMusculoskeletalNervousReproductiveRespiratoryUrinary
Sources & attribution
GPCRdbCC BY 4.0Human Protein AtlasCC BY-SA 4.0IUPHAR/BPS Guide to PHARMACOLOGYCC BY-SA 4.0ChEMBLCC BY-SA 4.0Open Targets PlatformCC0 1.0
Data redistributed under each source's licence. See Citation & licenses.