NPY5R

ATchem

Y5 receptor

Rhodopsin· Neuropeptide Y receptors· 445 aa
Development interest
42/ 100
Tchem

A potent ligand exists, but no approved drug.

420 refs·913 ligands·0 structures
Ligands
×20%
Literature
×30%
Disease evidence
×15%
Approved drugs
×20%
Structures
×15%
Signalling

Signal transduction

Primary G-protein transducer(s):

Gi/Goprimary

Canonical coupling; some receptors also signal through secondary transducers and β-arrestin. See GPCRdb couplings for full data.

At a glance

Key facts

Structures
0
Distinct ligands
913
Approved drugs
0
Disease links
200
Organ systems
8
Citations
420
AdiposeCardiovascularDigestiveEndocrineImmuneNervousReproductiveUrinary