TACR2
ATchemNK2 receptor
Rhodopsin· Tachykinin receptors· 398 aa
Development interest
46/ 100
Tchem
A potent ligand exists, but no approved drug.
628 refs·912 ligands·1 structures
Ligands
×20%
Literature
×30%
Disease evidence
×15%
Structures
×15%
Approved drugs
×20%
Signalling
Signal transduction
Primary G-protein transducer(s):
Gq/G11primary
Canonical coupling; some receptors also signal through secondary transducers and β-arrestin. See GPCRdb couplings for full data.
At a glance
Key facts
- Structures
- 1
- Distinct ligands
- 912
- Approved drugs
- 0
- Disease links
- 159
- Organ systems
- 6
- Citations
- 628
CardiovascularDigestiveMusculoskeletalNervousReproductiveUrinary
Sources & attribution
GPCRdbCC BY 4.0Human Protein AtlasCC BY-SA 4.0IUPHAR/BPS Guide to PHARMACOLOGYCC BY-SA 4.0ChEMBLCC BY-SA 4.0PubChem BioAssayPublic domainOpen Targets PlatformCC0 1.0
Data redistributed under each source's licence. See Citation & licenses.