NPY2R

ATchem

Y2 receptor

Rhodopsin· Neuropeptide Y receptors· 381 aa
Development interest
48/ 100
Tchem

A potent ligand exists, but no approved drug.

812 refs·916 ligands·5 structures
Ligands
×20%
Literature
×30%
Structures
×15%
Disease evidence
×15%
Approved drugs
×20%
Signalling

Signal transduction

Primary G-protein transducer(s):

Gi/Goprimary

Canonical coupling; some receptors also signal through secondary transducers and β-arrestin. See GPCRdb couplings for full data.

At a glance

Key facts

Structures
5
Distinct ligands
916
Approved drugs
0
Disease links
198
Organ systems
2
Citations
812
NervousReproductive