NPY4R

ATchem

Y4 receptor

Rhodopsin· Neuropeptide Y receptors· 375 aa
Development interest
35/ 100
Tchem

A potent ligand exists, but no approved drug.

137 refs·543 ligands·1 structures
Ligands
×20%
Literature
×30%
Structures
×15%
Disease evidence
×15%
Approved drugs
×20%
Signalling

Signal transduction

Primary G-protein transducer(s):

Gi/Goprimary

Canonical coupling; some receptors also signal through secondary transducers and β-arrestin. See GPCRdb couplings for full data.

At a glance

Key facts

Structures
1
Distinct ligands
543
Approved drugs
0
Disease links
34
Organ systems
4
Citations
137
DigestiveIntegumentaryMusculoskeletalReproductive