MC1R
ATclinMC1 receptor
Rhodopsin· Melanocortin receptors· 317 aa
Development interest
67/ 100
Tclin
An approved drug acts on this receptor.
2,176 refs·901 ligands·4 structures
Ligands
×20%
Disease evidence
×15%
Literature
×30%
Approved drugs
×20%
Structures
×15%
Signalling
Signal transduction
Primary G-protein transducer(s):
Gsprimary
Canonical coupling; some receptors also signal through secondary transducers and β-arrestin. See GPCRdb couplings for full data.
At a glance
Key facts
- Structures
- 4
- Distinct ligands
- 901
- Approved drugs
- 7
- Disease links
- 547
- Organ systems
- 11
- Citations
- 2,176
AdiposeCardiovascularDigestiveEndocrineImmuneIntegumentaryMusculoskeletalNervousReproductiveRespiratoryUrinary
Sources & attribution
GPCRdbCC BY 4.0Human Protein AtlasCC BY-SA 4.0IUPHAR/BPS Guide to PHARMACOLOGYCC BY-SA 4.0ChEMBLCC BY-SA 4.0PubChem BioAssayPublic domainOpen Targets PlatformCC0 1.0
Data redistributed under each source's licence. See Citation & licenses.