MRGPRX2
ATclinOrphanMRGPRX2
Rhodopsin· Class A orphans· 330 aa
Development interest
57/ 100
Tclin
An approved drug acts on this receptor.
487 refs·282 ligands·14 structures
Ligands
×20%
Structures
×15%
Approved drugs
×20%
Literature
×30%
Disease evidence
×15%
Signalling
Signal transduction
Primary G-protein transducer(s):
Gq/G11primary
Canonical coupling; some receptors also signal through secondary transducers and β-arrestin. See GPCRdb couplings for full data.
At a glance
Key facts
- Structures
- 14
- Distinct ligands
- 282
- Approved drugs
- 11
- Disease links
- 218
- Organ systems
- 0
- Citations
- 487
Sources & attribution
GPCRdbCC BY 4.0Human Protein AtlasCC BY-SA 4.0IUPHAR/BPS Guide to PHARMACOLOGYCC BY-SA 4.0ChEMBLCC BY-SA 4.0PubChem BioAssayPublic domainOpen Targets PlatformCC0 1.0
Data redistributed under each source's licence. See Citation & licenses.