MRGPRF
ATbioOrphanMRGPRF
Rhodopsin· Class A orphans· 343 aa
Development interest
13/ 100
Tbio
Biology is characterised, but no potent ligand.
18 refs·0 ligands·0 structures
Disease evidence
×15%
Literature
×30%
Ligands
×20%
Approved drugs
×20%
Structures
×15%
Signalling
Signal transduction
Primary G-protein transducer(s):
Gq/G11primary
Canonical coupling; some receptors also signal through secondary transducers and β-arrestin. See GPCRdb couplings for full data.
At a glance
Key facts
- Structures
- 0
- Distinct ligands
- 0
- Approved drugs
- 0
- Disease links
- 60
- Organ systems
- 11
- Citations
- 18
AdiposeCardiovascularDigestiveEndocrineImmuneIntegumentaryMusculoskeletalNervousReproductiveRespiratoryUrinary
Sources & attribution
GPCRdbCC BY 4.0Human Protein AtlasCC BY-SA 4.0ChEMBLCC BY-SA 4.0Open Targets PlatformCC0 1.0IUPHAR/BPS Guide to PHARMACOLOGYCC BY-SA 4.0
Data redistributed under each source's licence. See Citation & licenses.