MRGPRD
ATbioOrphanMRGPRD
Rhodopsin· Class A orphans· 321 aa
Development interest
22/ 100
Tbio
Biology is characterised, but no potent ligand.
98 refs·1 ligands·6 structures
Literature
×30%
Structures
×15%
Disease evidence
×15%
Ligands
×20%
Approved drugs
×20%
Signalling
Signal transduction
Primary G-protein transducer(s):
Gq/G11primary
Canonical coupling; some receptors also signal through secondary transducers and β-arrestin. See GPCRdb couplings for full data.
At a glance
Key facts
- Structures
- 6
- Distinct ligands
- 1
- Approved drugs
- 0
- Disease links
- 908
- Organ systems
- 0
- Citations
- 98
Sources & attribution
GPCRdbCC BY 4.0Human Protein AtlasCC BY-SA 4.0IUPHAR/BPS Guide to PHARMACOLOGYCC BY-SA 4.0ChEMBLCC BY-SA 4.0Open Targets PlatformCC0 1.0
Data redistributed under each source's licence. See Citation & licenses.