HRH4

ATclin

H4 receptor

Rhodopsin· Histamine receptors· 390 aa
Development interest
57/ 100
Tclin

An approved drug acts on this receptor.

491 refs·908 ligands·10 structures
Ligands
×20%
Literature
×30%
Structures
×15%
Approved drugs
×20%
Disease evidence
×15%
Signalling

Signal transduction

Primary G-protein transducer(s):

Gi/Goprimary

Canonical coupling; some receptors also signal through secondary transducers and β-arrestin. See GPCRdb couplings for full data.

At a glance

Key facts

Structures
10
Distinct ligands
908
Approved drugs
6
Disease links
560
Organ systems
0
Citations
491