GPRC5D
CTclinOrphanGPRC5D
Glutamate· Class C Orphans· 345 aa
Development interest
34/ 100
Tclin
An approved drug acts on this receptor.
308 refs·1 ligands·2 structures
Disease evidence
×15%
Literature
×30%
Structures
×15%
Approved drugs
×20%
Ligands
×20%
Signalling
Signal transduction
Primary G-protein coupling is not curated for GPRC5D in Helix7. See GPCRdb couplings for transducer data on this receptor.
At a glance
Key facts
- Structures
- 2
- Distinct ligands
- 1
- Approved drugs
- 1
- Disease links
- 58
- Organ systems
- 5
- Citations
- 308
DigestiveImmuneIntegumentaryReproductiveRespiratory
Sources & attribution
GPCRdbCC BY 4.0Human Protein AtlasCC BY-SA 4.0IUPHAR/BPS Guide to PHARMACOLOGYCC BY-SA 4.0ChEMBLCC BY-SA 4.0Open Targets PlatformCC0 1.0
Data redistributed under each source's licence. See Citation & licenses.