GPBAR1

ATclin

GPBA receptor

Rhodopsin· Bile acid receptors· 330 aa
Development interest
49/ 100
Tclin

An approved drug acts on this receptor.

332 refs·909 ligands·5 structures
Ligands
×20%
Literature
×30%
Structures
×15%
Approved drugs
×20%
Disease evidence
×15%
Signalling

Signal transduction

Primary G-protein coupling is not curated for GPBAR1 in Helix7. See GPCRdb couplings for transducer data on this receptor.

At a glance

Key facts

Structures
5
Distinct ligands
909
Approved drugs
3
Disease links
526
Organ systems
10
Citations
332
AdiposeCardiovascularDigestiveEndocrineImmuneIntegumentaryMusculoskeletalReproductiveRespiratoryUrinary