DRD3

ATclin

D3 receptor

Rhodopsin· Dopamine receptors· 400 aa
Development interest
76/ 100
Tclin

An approved drug acts on this receptor.

3,143 refs·923 ligands·6 structures
Ligands
×20%
Approved drugs
×20%
Disease evidence
×15%
Literature
×30%
Structures
×15%
Signalling

Signal transduction

Primary G-protein transducer(s):

Gi/Goprimary

Canonical coupling; some receptors also signal through secondary transducers and β-arrestin. See GPCRdb couplings for full data.

At a glance

Key facts

Structures
6
Distinct ligands
923
Approved drugs
47
Disease links
324
Organ systems
1
Citations
3,143
Nervous