DRD2
ATclinD2 receptor
Rhodopsin· Dopamine receptors· 443 aa
Development interest
82/ 100
Tclin
An approved drug acts on this receptor.
11,743 refs·548 ligands·8 structures
Approved drugs
×20%
Ligands
×20%
Disease evidence
×15%
Literature
×30%
Structures
×15%
Signalling
Signal transduction
Primary G-protein transducer(s):
Gi/Goprimary
Canonical coupling; some receptors also signal through secondary transducers and β-arrestin. See GPCRdb couplings for full data.
At a glance
Key facts
- Structures
- 8
- Distinct ligands
- 548
- Approved drugs
- 70
- Disease links
- 1797
- Organ systems
- 6
- Citations
- 11,743
DigestiveEndocrineMusculoskeletalNervousReproductiveUrinary
Sources & attribution
GPCRdbCC BY 4.0Human Protein AtlasCC BY-SA 4.0IUPHAR/BPS Guide to PHARMACOLOGYCC BY-SA 4.0ChEMBLCC BY-SA 4.0Open Targets PlatformCC0 1.0
Data redistributed under each source's licence. See Citation & licenses.