CX3CR1
ATclinCX3CR1
Rhodopsin· Chemokine receptors· 355 aa
Development interest
58/ 100
Tclin
An approved drug acts on this receptor.
3,860 refs·405 ligands·2 structures
Ligands
×20%
Literature
×30%
Disease evidence
×15%
Approved drugs
×20%
Structures
×15%
Signalling
Signal transduction
Primary G-protein transducer(s):
Gi/Goprimary
Canonical coupling; some receptors also signal through secondary transducers and β-arrestin. See GPCRdb couplings for full data.
At a glance
Key facts
- Structures
- 2
- Distinct ligands
- 405
- Approved drugs
- 4
- Disease links
- 1886
- Organ systems
- 11
- Citations
- 3,860
AdiposeCardiovascularDigestiveEndocrineImmuneIntegumentaryMusculoskeletalNervousReproductiveRespiratoryUrinary
Sources & attribution
GPCRdbCC BY 4.0Human Protein AtlasCC BY-SA 4.0IUPHAR/BPS Guide to PHARMACOLOGYCC BY-SA 4.0ChEMBLCC BY-SA 4.0PubChem BioAssayPublic domainOpen Targets PlatformCC0 1.0
Data redistributed under each source's licence. See Citation & licenses.