CCR2
ATclinCCR2
Rhodopsin· Chemokine receptors· 374 aa
Development interest
62/ 100
Tclin
An approved drug acts on this receptor.
6,175 refs·915 ligands·4 structures
Ligands
×20%
Literature
×30%
Disease evidence
×15%
Structures
×15%
Approved drugs
×20%
Signalling
Signal transduction
Primary G-protein transducer(s):
Gi/Goprimary
Canonical coupling; some receptors also signal through secondary transducers and β-arrestin. See GPCRdb couplings for full data.
At a glance
Key facts
- Structures
- 4
- Distinct ligands
- 915
- Approved drugs
- 1
- Disease links
- 1925
- Organ systems
- 10
- Citations
- 6,175
AdiposeCardiovascularDigestiveEndocrineImmuneIntegumentaryMusculoskeletalReproductiveRespiratoryUrinary
Sources & attribution
GPCRdbCC BY 4.0Human Protein AtlasCC BY-SA 4.0IUPHAR/BPS Guide to PHARMACOLOGYCC BY-SA 4.0ChEMBLCC BY-SA 4.0PubChem BioAssayPublic domainOpen Targets PlatformCC0 1.0
Data redistributed under each source's licence. See Citation & licenses.