ADRA2B
ATclinα2B-adrenoceptor
Rhodopsin· Adrenoceptors· 450 aa
Development interest
66/ 100
Tclin
An approved drug acts on this receptor.
190 refs·519 ligands·2 structures
Approved drugs
×20%
Ligands
×20%
Disease evidence
×15%
Literature
×30%
Structures
×15%
Signalling
Signal transduction
Primary G-protein transducer(s):
Gi/Goprimary
Canonical coupling; some receptors also signal through secondary transducers and β-arrestin. See GPCRdb couplings for full data.
At a glance
Key facts
- Structures
- 2
- Distinct ligands
- 519
- Approved drugs
- 93
- Disease links
- 518
- Organ systems
- 10
- Citations
- 190
AdiposeCardiovascularDigestiveEndocrineImmuneIntegumentaryMusculoskeletalNervousReproductiveUrinary
Sources & attribution
GPCRdbCC BY 4.0Human Protein AtlasCC BY-SA 4.0IUPHAR/BPS Guide to PHARMACOLOGYCC BY-SA 4.0ChEMBLCC BY-SA 4.0Open Targets PlatformCC0 1.0
Data redistributed under each source's licence. See Citation & licenses.