ACKR3
ATclinACKR3
Rhodopsin· Chemokine receptors· 362 aa
Development interest
53/ 100
Tclin
An approved drug acts on this receptor.
289 refs·903 ligands·7 structures
Ligands
×20%
Disease evidence
×15%
Literature
×30%
Structures
×15%
Approved drugs
×20%
Signalling
Signal transduction
Primary G-protein transducer(s):
Gi/Goprimary
Canonical coupling; some receptors also signal through secondary transducers and β-arrestin. See GPCRdb couplings for full data.
At a glance
Key facts
- Structures
- 7
- Distinct ligands
- 903
- Approved drugs
- 1
- Disease links
- 1629
- Organ systems
- 11
- Citations
- 289
AdiposeCardiovascularDigestiveEndocrineImmuneIntegumentaryMusculoskeletalNervousReproductiveRespiratoryUrinary
Sources & attribution
GPCRdbCC BY 4.0Human Protein AtlasCC BY-SA 4.0IUPHAR/BPS Guide to PHARMACOLOGYCC BY-SA 4.0ChEMBLCC BY-SA 4.0PubChem BioAssayPublic domainOpen Targets PlatformCC0 1.0
Data redistributed under each source's licence. See Citation & licenses.