ADORA3

ATclin

A3 receptor

Rhodopsin· Adenosine receptors· 318 aa
Development interest
61/ 100
Tclin

An approved drug acts on this receptor.

622 refs·971 ligands·2 structures
Ligands
×20%
Disease evidence
×15%
Literature
×30%
Approved drugs
×20%
Structures
×15%
Signalling

Signal transduction

Primary G-protein transducer(s):

Gi/Goprimary

Canonical coupling; some receptors also signal through secondary transducers and β-arrestin. See GPCRdb couplings for full data.

At a glance

Key facts

Structures
2
Distinct ligands
971
Approved drugs
8
Disease links
718
Organ systems
10
Citations
622
AdiposeCardiovascularDigestiveEndocrineImmuneMusculoskeletalNervousReproductiveRespiratoryUrinary