ADORA2A
ATclinA2A receptor
Rhodopsin· Adenosine receptors· 412 aa
Development interest
74/ 100
Tclin
An approved drug acts on this receptor.
2,664 refs·978 ligands·80 structures
Ligands
×20%
Structures
×15%
Disease evidence
×15%
Literature
×30%
Approved drugs
×20%
Signalling
Signal transduction
Primary G-protein transducer(s):
Gsprimary
Canonical coupling; some receptors also signal through secondary transducers and β-arrestin. See GPCRdb couplings for full data.
At a glance
Key facts
- Structures
- 80
- Distinct ligands
- 978
- Approved drugs
- 6
- Disease links
- 957
- Organ systems
- 11
- Citations
- 2,664
AdiposeCardiovascularDigestiveEndocrineImmuneIntegumentaryMusculoskeletalNervousReproductiveRespiratoryUrinary
Sources & attribution
GPCRdbCC BY 4.0Human Protein AtlasCC BY-SA 4.0IUPHAR/BPS Guide to PHARMACOLOGYCC BY-SA 4.0ChEMBLCC BY-SA 4.0PubChem BioAssayPublic domainOpen Targets PlatformCC0 1.0
Data redistributed under each source's licence. See Citation & licenses.