HTR2B
ATclin5-HT2B receptor
Rhodopsin· 5-Hydroxytryptamine receptors· 481 aa
Development interest
73/ 100
Tclin
An approved drug acts on this receptor.
481 refs·903 ligands·11 structures
Ligands
×20%
Approved drugs
×20%
Disease evidence
×15%
Literature
×30%
Structures
×15%
Signalling
Signal transduction
Primary G-protein transducer(s):
Gq/G11primary
Canonical coupling; some receptors also signal through secondary transducers and β-arrestin. See GPCRdb couplings for full data.
At a glance
Key facts
- Structures
- 11
- Distinct ligands
- 903
- Approved drugs
- 73
- Disease links
- 332
- Organ systems
- 8
- Citations
- 481
CardiovascularDigestiveEndocrineImmuneMusculoskeletalNervousReproductiveUrinary
Sources & attribution
GPCRdbCC BY 4.0Human Protein AtlasCC BY-SA 4.0IUPHAR/BPS Guide to PHARMACOLOGYCC BY-SA 4.0ChEMBLCC BY-SA 4.0PubChem BioAssayPublic domainOpen Targets PlatformCC0 1.0
Data redistributed under each source's licence. See Citation & licenses.