HTR1A
ATclin5-HT1A receptor
Rhodopsin· 5-Hydroxytryptamine receptors· 422 aa
Development interest
78/ 100
Tclin
An approved drug acts on this receptor.
4,347 refs·987 ligands·13 structures
Ligands
×20%
Approved drugs
×20%
Disease evidence
×15%
Literature
×30%
Structures
×15%
Signalling
Signal transduction
Primary G-protein transducer(s):
Gi/Goprimary
Canonical coupling; some receptors also signal through secondary transducers and β-arrestin. See GPCRdb couplings for full data.
At a glance
Key facts
- Structures
- 13
- Distinct ligands
- 987
- Approved drugs
- 42
- Disease links
- 489
- Organ systems
- 2
- Citations
- 4,347
NervousReproductive
Sources & attribution
GPCRdbCC BY 4.0Human Protein AtlasCC BY-SA 4.0IUPHAR/BPS Guide to PHARMACOLOGYCC BY-SA 4.0ChEMBLCC BY-SA 4.0PubChem BioAssayPublic domainOpen Targets PlatformCC0 1.0
Data redistributed under each source's licence. See Citation & licenses.